Backpacking=schweeeeeeeet…

So, Nathan and I made it back alive from the backcountry in North Carolina…here are some pictures

Overall, the trip was really fun.? We made it in on Saturday night and camped at the park…took about 10 hrs to get there…? We got started on Sunday morning and made the ascent of Mt. Sterling…6.2 miles and 4100 feet up…and it sucked…? Believe you me, I almost didn’t make it…and once I sat down at the top, I couldn’t walk for a good 10 minutes…? The descent was split between the next two days, so I got some blisters on the way down…but the scenery was unbelievable, from scenic overlooks to waterfalls…everything was gorgeous…? The weather was generally 75 F for the first few days, but a T-storm came through on Monday night and cooled things down, yet it was still in the mid- to upper-40s for the remainder of the hike, so it was still quite comfortable.

Regardless, it was a great trip…thanks for going, Nathan…

Ready for the break…

Yeah, had a test today…went alright, generally… I had that presentation last week, which could have gone better, but is otherwise done… And, I’ve got an exam next Friday…

But…Spring Break awaits. And I’m going backpacking with Nathan again. Likely, we’re going to Mt. Sterling, which is close to Cherokee, NC. The interesting thing is that, as you may note from the link, there are bears at campsite 39. That should be fun. Nathan, bring your handgun.

Anyway, I’m more than ready for these next two weeks to be over so I can take a little break. Then, I’ve “only” got two more exams before the semester is over and I have summer vacation. On the other hand, I start lab work this summer, so I really don’t get a vacation…

Is it too early to be thinking of summer vacation?

Under pressure…

So, I’ve got that presentation on Wednesday…and I’ve got to pre-present it for Dr. Samson tomorrow to make sure I’m on the right track…which I hopefully am. I’ve been working on it a lot today and, no doubt, I’ll continue working on it until late tonight…

This thing worries me. Not because of the material. Not because I’ll be presenting it in front of Ph.Ds who will ask me questions. Not because the grade for the semester is made up of this one presentation. Nope. Because, for the most part, this is the first presentation that I have where anyone can attend and see how I do. If I do a great job, then the professors who are watching will think that much more of me. If I don’t do well, then it could very well set the tone for the remainder of my graduate career.

No pressure…

A milestone…

So, for those who have ever sat next to me in class, you know I have Solitaire on my Sony Clie (a Palm device, for those who don’t know…).? Finally, I “won” $100,000, which means that the game no longer keeps count, since it can’t go over 5 digits.? Therefore, I must restart the game at $0.? But before I do, I mark the occasion with some stats that have been recorded since beginning the game over a year ago:

Games played: 1227

Games won: 500

Games Lost: 727

Percent Won: 40.75%

Longest Win Streak: 6

Longest Loss Streak: 12

Average Game Time: 1:59

Total Time Played: 1d 16h 52m

Shortest Win Time: 1:20

Highest Score: $100041

…time to reset…

So, I was sitting in class…

…and Dr. Ryerse was talking to us about Gap Junctions. Basically, these are connections between cells that are made up of proteins. Think of them like connecting two pieces of cloth with a hollow rivet… They are very important in a variety of cellular functions, but perhaps most importantly, in synchronizing all of the cells in the heart (and muscle in general) to make one single contraction and pump our blood.

Anyway, in talking about these, he brought up a few points (most of which I can’t remember…) that got me thinking about how much of ourselves we know nothing about. In the physical sense, our bodies “just work”…but how and why? I mean, we go walking around every day and the general public doesn’t know (or care…) about how the cells in our heart know how to contract at the same time and pump our blood.But we’ve been working on “science,” in the general sense of the word, for thousands of years yet we’ve only scratched the surface.
Shouldn’t we care about these things? Shouldn’t we be more interested in learning all that there is to know about our bodies, so we know how to fix the problems there, rather than the problems between bodies in foreign countries? If I remember right, Bush plans on cutting a variety of programs, generally social, educational and scientific interests, in favor of more money to finance his Iraq vendetta. Does this make sense?
I guess it’s just human nature, but here’s the point: people don’t care how something works, only that it continues to work. People don’t care about science until it affects them. Funding for scientific endeavours is only readily available to people working on health-related fields, while funding for other research (such as ecology, sociology, etc.) is harder to come by. We save the minimal amount of funding to pay for “important” things like helping fix lung cancer (caused by cigarettes) or funding faster propulsion (so we can blow up other countries) or funding research into lower emission vehicles (because we have to drive big SUVs rather than using the smaller vehicles we already have).

Seriously, I think if the USA just saved a third of the money being poured into Iraq and other worthless ventures (congressional salaries, military stockpiling, tax cuts for the rich, etc.) and instead put it into general scientific (physics, biology, chemistry…) and social (arts, humanities…) research, the world would get a lot better really quickly.

At the very least, we, as a culture, would be seen as less hypocritical in the eyes of our enemies…’cause that’d solve a lot of other problems…

…it’s amazing what thoughts can come out of a discussion on gap junctions, eh?

One more rotation…

So on Monday afternoon, I’m starting my fourth (and final?) rotation with Dr. Heather Macarthur. I’m actually pretty excited about this rotation since, for the first time, I’m doing research in stuff I’m pretty interested in. I wanted to go to SLU because of the research going on in Dr. Westfall’s lab, and Dr. Macarthur works really closely with him…thus, the research is similar…

Here’s the rundown: Parkinson’s Disease is characterized by a loss of motor control because (so far as we know) neurons localized in your brain (acround the cerebellum and nucleus accumbens…I think…) die for some reason. It is thought that one way these neurons die is due to oxidative stress. For those of you who know anything about chemistry, there are things called “free radicals,” which are analogues of known compounds that are missing an electron…hence, they “want” to bind with something else by any means necessary. In the body, these free radicals can do a lot of damage and can end up damaging or killing a given cell. We take antioxidants (and we have natural ones in our bodies…) to prevent damage by free radicals…surely you’ve heard of those…
Well, dopamine is a neurotransmitter that is important in controlling our body movements in our brain (among other functions). Apparently, there is a “version” of dopamine known as dopaminochrome that is essentially a dopamine free radical… If this stuff accumulates in your brain, it can kill off the cells it inhabits…and in Parkinson’s patients, it is possible that this molecule ends up accumulating where dopamine is normally localized.

(side note: as Dr. Macarthur pointed out to me, we normally think of Parkinson’s patients as moving uncontrollably. Actually, Parkinson’s patients would normally not be able to move at all, but the drugs we give them flood the cells with dopamine, causing more uncontrollable movement. I didn’t know that…thought it was interesting… :-P)

Anyway, Dr. Macarthur’s lab works with dopaminochrome in rats, detecting it and analyzing its effects. Actually, they use a drug that causes Parkinson’s-like effects in rats or cell lines, which allows for testing. I’m not sure exactly what I’ll end up doing in her lab, but I think I’ll be messing with an HPLC (high pressure liquid chromatography) that’s been modified to detect dopaminochrome in a variety of situations… If all goes well, then I’ll be doing this stuff for the next 4 years until I get a Ph.D… 😛

To pose a question…

I was leaving class today and had a random thought, which I thought I’d record here and see if I got any responses. The question is: why is cussing/swearing bad? I mean, they’re words. Simply words. Why is it bad to say “shit” but not “poop?” They have the same meaning, but one is considered “worse” that the other. I know that, as a stigma, it was/is bad to “say the Lord’s name in vain,” as the Ten Commandments dictate. But “shit” isn’t exactly in the Bible on a list of “you can’t say these things.” Are they simply social constructs? …which brings up the question of when they’ll be considered alright to say, because while “damn” wasn’t allowed on TV or socially 50 years ago, or “bitch” even, they are more “socially acceptable” now. On the other hand, saying “damnit” could be put in the “Lord’s name in vain” column, according to some.

So yeah, what the hell? 😉 (that was my moment of irony for this posting…don’t blink, ’cause you may miss it)

On getting fit(ter)…

So yeah, Nathan and I are going backpacking over Spring Break again, so I’m trying to work out a bit more than I had been before. Last year, I did alright, but certainly should have been able to hike further and faster. I’m back to being able to jog for 20 min straight at a pace of 6.5 mph, which is a little over a nine minute mile. My goal is to be jogging for 20 min at 7.5 mph, which is about an eight minute mile. I think, by mid-March, that should be entirely attainable.

On a related note, my new frame pack arrived yesterday…5600 ci Kelty Red Cloud for about $100, so it was a steal ($75 less than at REI). I’m excited to get to use it! I still need to get a water filter though, since a). mine broke last year and b). I can’t trust Nathan to bring iodine tablets to cover our asses when we get stuck in the middle of nowhere and have to boil water to stay alive.

…but that’s another story…

Eeeeesh…

So, Brooke and I are watching “Monk,” which is one of the best shows ever made as far as I’m concerned…and we were looking up previous things that Tony Shaloub has been in… Do you realize that “Wings,” for which he is best known, started in 1990 and ended in 1997?? Almost 10 years ago now?!? Do you realize how old I am?!?!?

…dammit…

College doesn't teach you things

So, today I heard on Rover’s Morning Glory (replaced Howard Stern here in the midwest…) that this group called the American Institutes for Research published a study about college students and how they aren’t prepared for life after graduation; the full results of the study are published online. Here are a few highlights:

  • Students in 2- and 4-year colleges have the greatest difficulty with quantitative literacy: approximately 30 percent of students in 2-year institutions and nearly 20 percent of students in 4-year institutions have only Basic quantitative literacy. Basic skills are those necessary to compare ticket prices or calculate the cost of a sandwich and a salad from a menu.
  • There are no significant differences in the literacy of students graduating from public and private institutions. Additionally, in assessing literacy levels, there are no differences between part-time and full-time students. No overall relationship exists between literacy and the length of time it takes to earn a degree, or between literacy and an academic major.
  • Literacy level is significantly higher among students who say their coursework places a strong emphasis on applying theories or concepts to practical problems, in comparison to students who say their coursework rarely touch on these skills.

Yeah, I’ve kinda wondered about this for awhile…? I mean, most college students (in my opinion) don’t think they really learn anything useful, or things that pertain to their career (for example, taking a class like LAS Calculus or Writing as Critical Thinking).? Personally, most of those “worthless” classes for me were silly because I had the same thing or better in high school, so I didn’t see why I needed to take the same thing again.? On the other hand, I consider Hickman High to be amongst the top high schools in the state, which is a far cry from some high schools with fewer resources to draw from in more rural areas.

I guess I’m not sure what I think about these results. I think it’s pretty dumb that you can graduate from college without knowing how to tell how many more miles you can drive when your car gets 30 mi/gal and you have 4 gallons of gas left (this study pointed out that there are college graduates who can’t figure that out…and it’s an unbelievably high percentage…). I guess that classes should try and incorporate more “real life” examples into their classes, or perhaps even have a required freshman-year course titled “Life: How to not be an idiot.”

On the other hand, I guess the best way to learn about life is just to live. There are some things you simply can’t learn from coursework…but seriously…if you don’t know how to figure out how much further you can drive on a half tank of gas, you’re an idiot and don’t deserve that degree…